Tenecteplase
A single-bolus thrombolytic dosed by weight for STEMI; also used in stroke per protocol.
On this page
STEMI dose (single IV bolus)
| Weight | Dose |
|---|---|
| Under 60 kg | 30 mg |
| 60–69 kg | 35 mg |
| 70–79 kg | 40 mg |
| 80–89 kg | 45 mg |
| 90 kg and over | 50 mg |
Many guidelines give half the dose in patients aged 75 and over.
Stroke
0.25 mg/kg (max 25 mg) single bolus, per stroke protocol.
Cautions
Same contraindications as other thrombolytics: active bleeding, recent stroke, surgery or trauma, aortic dissection.
Frequently asked questions
How is tenecteplase given?
As a single IV bolus over 5–10 seconds, dosed by body weight.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.