Enoxaparin
Prophylaxis 40 mg SC daily. Treatment 1 mg/kg twice daily or 1.5 mg/kg once daily. Reduce in kidney failure.
Common brands in Pakistan: Clexane. Brand availability changes; check with your pharmacy.
On this page
Dose
| Indication | Dose |
|---|---|
| VTE prophylaxis | 40 mg SC once daily (20 mg if creatinine clearance below 30) |
| DVT/PE treatment | 1 mg/kg SC every 12 hours, or 1.5 mg/kg once daily |
| ACS (NSTEMI) | 1 mg/kg SC every 12 hours |
| Creatinine clearance below 30 (treatment) | 1 mg/kg once daily |
Cautions
- Bleeding; check platelets if on it for more than a few days.
- Stop 12 hours (prophylaxis) or 24 hours (treatment) before spinal anaesthesia or surgery.
- Safe in pregnancy.
Frequently asked questions
What is the prophylactic dose of enoxaparin?
40 mg SC once daily, or 20 mg if creatinine clearance is below 30.
Used in these guides
- Acute coronary syndrome (heart attack)
- Acute heart failure and pulmonary oedema
- Acute pancreatitis
- Calf pain and deep vein thrombosis (DVT)
- Guillain–Barré syndrome
- Hip (neck of femur) fracture
- Inflammatory bowel disease flares
- Low oxygen saturations on the ward
- Post-operative complications
- Pulmonary embolism
- Spinal cord compression
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.