Apixaban
VTE: 10 mg twice daily for 7 days, then 5 mg twice daily. AF: 5 mg twice daily (2.5 mg if dose-reduction criteria met).
Common brands in Pakistan: Eliquis. Brand availability changes; check with your pharmacy.
On this page
Dose
Cautions
- Avoid if creatinine clearance below 15; caution 15–29.
- Not for metal heart valves or antiphospholipid syndrome.
- Bleeding; interactions with strong CYP3A4 and P-gp inhibitors and inducers (rifampicin).
Frequently asked questions
When is apixaban 2.5 mg used in AF?
When at least 2 of these apply: age 80 or over, weight 60 kg or less, serum creatinine 1.5 mg/dL (133 µmol/L) or more.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.
For FCPS Part 1
Revising for FCPS Part 1? Apixaban is covered in our textbook chapter Anticoagulants and antiplatelets, with practice MCQs.