Rivaroxaban

VTE: 15 mg twice daily for 21 days, then 20 mg once daily with food. AF: 20 mg daily (15 mg if creatinine clearance 15–49).

Direct oral anticoagulant (factor Xa inhibitor)Reviewed October 2026

Common brands in Pakistan: Xarelto. Brand availability changes; check with your pharmacy.

On this page

Dose

IndicationDose
DVT/PE treatment15 mg twice daily for 21 days, then 20 mg once daily
AF stroke prevention20 mg once daily (15 mg if creatinine clearance 15–49)

Take 15 mg and 20 mg doses with food.

Cautions

  • Avoid if creatinine clearance below 15.
  • Not for metal valves or antiphospholipid syndrome.

Frequently asked questions

Should rivaroxaban be taken with food?

Yes, the 15 mg and 20 mg doses must be taken with food for proper absorption.

Used in these guides

Sources

  1. Drugs.com: Rivaroxaban dosage

Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.