Carboprost
Third-line uterotonic: 250 micrograms deep IM every 15 minutes, up to 8 doses. Avoid in asthma.
Common brands in Pakistan: Hemabate. Brand availability changes; check with your pharmacy.
On this page
Dose
250 micrograms deep IM every 15 minutes if needed, maximum 8 doses (2 mg). Intramyometrial injection only by a senior obstetrician.
Cautions
- Avoid in asthma (bronchospasm).
- Diarrhoea, vomiting, fever, flushing.
- Needs a fridge; often unavailable in smaller hospitals.
Frequently asked questions
When is carboprost used?
When bleeding continues despite oxytocin, ergometrine (if suitable) and tranexamic acid.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.
For FCPS Part 1
Revising for FCPS Part 1? Carboprost is covered in our textbook chapter Oxytocics and prostaglandins, with practice MCQs.