Ergometrine

Second-line for uterine atony: 0.2–0.5 mg IM. Avoid in high BP, pre-eclampsia and heart disease.

Ergot alkaloid uterotonicReviewed October 2026
On this page

Dose

IndicationDose
PPH (uterine atony)0.2–0.5 mg IM (or 0.2 mg slow IV in emergencies), repeat after 15 minutes if needed; maximum 1 mg
Syntometrine (5 units oxytocin + 0.5 mg ergometrine)1 mL IM

Contraindications

High BP, pre-eclampsia or eclampsia, heart disease, severe liver or kidney disease.

Side effects

Nausea, vomiting, high BP, headache, coronary spasm.

Frequently asked questions

Why is ergometrine avoided in pre-eclampsia?

It raises blood pressure sharply and can cause strokes or fits.

Used in these guides

Sources

  1. Drugs.com: Ergonovine and methylergonovine monograph
  2. WHO: Recommendations for postpartum haemorrhage

Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.

For FCPS Part 1

Revising for FCPS Part 1? Ergometrine is covered in our textbook chapter Oxytocics and prostaglandins, with practice MCQs.