Sumatriptan

A triptan for migraine attacks. 50 mg at onset, repeat after 2 hours if it returns, max 300 mg a day.

Triptan (5-HT1 agonist)Reviewed October 2026
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Dose

50 mg orally at the start of the headache (25–100 mg). If the headache returns, repeat after at least 2 hours; max 300 mg in 24 hours. Don't take a second dose for the same attack if the first didn't work.

Cautions

  • Avoid in ischaemic heart disease, previous stroke, uncontrolled BP, peripheral vascular disease.
  • Chest tightness, tingling, flushing.
  • Triptans on 10 or more days a month cause medication-overuse headache.

Frequently asked questions

Can sumatriptan be repeated?

Yes, after at least 2 hours if the migraine returns, up to 300 mg a day.

Used in these guides

Sources

  1. Drugs.com: Sumatriptan dosage

Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.