Naproxen

An NSAID with a longer action. 500 mg twice daily for acute gout; 250–500 mg twice daily for pain.

NSAIDReviewed October 2026
On this page

Uses

  • Acute gout, back pain, musculoskeletal pain, period pain.

Adult dose

IndicationDose
Acute gout500 mg twice daily (some regimens 750 mg then 250 mg 8-hourly) until settled
Pain250–500 mg twice daily with food

Kidney and liver

Avoid in kidney impairment.

Pregnancy and breastfeeding

Avoid in pregnancy.

Side effects and cautions

  • Gastrointestinal bleeding (give a PPI if at risk), AKI, fluid retention, high BP.

Frequently asked questions

What is the naproxen dose for gout?

500 mg twice daily with food for a few days, with a PPI if needed.

Used in these guides

Sources

  1. Drugs.com: Naproxen dosage

Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.