Head and neck anatomy
Head, neck and spine anatomy: cranial nerves, neck, thyroid, cord and lumbar puncture
Cranial nerve lesions, neck triangles, carotid landmarks, thyroid surgery anatomy, cord syndromes and lumbar puncture for FCPS Part 1. The anatomy is taught through the procedures and bedside signs that examiners build questions on.
One of the most tested topics in past papers
Cranial nerves at the bedside
| Nerve | Key function | Lesion sign |
|---|---|---|
| I | Smell (cribriform plate) | Anosmia after head injury, Kallmann syndrome |
| II | Vision; afferent limb of light reflex | Field defect, relative afferent pupillary defect |
| III | Most eye muscles, levator, pupil constriction | Eye down and out, ptosis, dilated pupil. Pupil involved (compressive, e.g. posterior communicating artery aneurysm) versus pupil spared (diabetic ischaemia of central fibres) |
| IV | Superior oblique | Vertical diplopia on reading or going downstairs; head tilts away from the lesion |
| V | Facial sensation, mastication, afferent corneal reflex | Jaw deviates towards the lesion |
| VI | Lateral rectus | Horizontal diplopia; long intracranial course makes it a false localising sign of raised ICP |
| VII | Facial expression, taste anterior two-thirds, stapedius, glands | LMN (Bell palsy): whole half of face. UMN (stroke): forehead spared (bilateral cortical supply) |
| VIII | Hearing, balance | Cerebellopontine angle tumour (with V and VII) |
| IX | Taste and sensation posterior third of tongue, gag afferent, carotid sinus | Lost gag |
| X | Palate, larynx, gag efferent | Uvula deviates away from the lesion; hoarseness |
| XI | Sternocleidomastoid, trapezius | Weak shrug after posterior triangle node biopsy |
| XII | Tongue | Tongue deviates towards the lesion |
- Lacrimation pathway: superior salivatory nucleus, facial nerve, greater petrosal nerve (preganglionic parasympathetic), nerve of the pterygoid canal, pterygopalatine ganglion, then zygomatic and lacrimal nerves. A facial lesion proximal to the geniculate ganglion gives a dry eye.
- Bulbar palsy (LMN: wasted fasciculating tongue) versus pseudobulbar palsy (UMN: spastic tongue, brisk jaw jerk, emotional lability).
- Horner syndrome: partial ptosis, miosis, anhidrosis; Pancoast tumour, carotid dissection, lateral medullary syndrome, neck surgery.
- Cavernous sinus: III, IV, V1, V2 in the lateral wall; VI and the internal carotid artery inside the sinus, so VI is affected first.
Visual pathway lesions
| Lesion site | Field defect |
|---|---|
| Optic nerve | Monocular blindness |
| Optic chiasm (pituitary adenoma) | Bitemporal hemianopia |
| Optic tract | Contralateral homonymous hemianopia |
| Temporal lobe (Meyer loop) | Contralateral upper quadrantanopia |
| Parietal radiation | Contralateral lower quadrantanopia |
| Occipital cortex | Homonymous hemianopia with macular sparing |
Neck triangles, vessels and airway
- Posterior triangle (sternocleidomastoid, trapezius, clavicle): roof of investing fascia; floor of muscles covered by prevertebral fascia (splenius, levator scapulae, scalenes). The accessory nerve runs superficially across it, just under the investing layer, so it is easily cut in node biopsy. Other contents: brachial plexus trunks, subclavian artery, external jugular vein, and the transverse cervical and suprascapular arteries, branches of the thyrocervical trunk (from the first part of the subclavian artery).
- Carotid sheath: common carotid medial, internal jugular vein lateral, vagus behind between them; bifurcation at the upper border of the thyroid cartilage (C3–C4).
- Compressing the common carotid: press backwards against the anterior (carotid) tubercle of the C6 transverse process, the most prominent cervical tubercle, at the level of the cricoid. The first rib is the landmark for the subclavian artery, not the carotid.
- Carotid sinus massage stretches the baroreceptors, increasing their firing; the glossopharyngeal afferents raise vagal (parasympathetic) output and slow the heart, which can end a supraventricular tachycardia. Avoid it in elderly patients with bruits.
- Internal jugular cannulation: apex of the triangle between the two heads of sternocleidomastoid and the clavicle, lateral to the carotid pulse, aiming at the ipsilateral nipple; right side preferred. Risks: carotid puncture, pneumothorax, air embolism. Subclavian route carries the highest pneumothorax risk and lowest infection risk.
- Cricothyroidotomy goes through the avascular cricothyroid membrane; tracheostomy through rings 2–4 (thyroid isthmus overlies them).
- Larynx: all intrinsic muscles are supplied by the recurrent laryngeal nerve except cricothyroid (external laryngeal nerve). Posterior cricoarytenoid is the only abductor. The left RLN hooks under the aortic arch (affected by lung cancer, aneurysm, enlarged left atrium).
- Pharyngeal pouch (Zenker diverticulum): arises posteriorly through Killian dehiscence, the weak area between the thyropharyngeal and cricopharyngeal parts of the inferior constrictor. Elderly patient with dysphagia, regurgitation of undigested food, halitosis and a gurgling neck swelling.
Thyroid: nodules and surgical anatomy
- Solitary nodule in a euthyroid patient (normal TSH): next step is ultrasound with FNAC. Isotope scanning is used when TSH is low, to look for a hot nodule.
- Toxic multinodular goitre: elderly patient with long-standing goitre who becomes thyrotoxic; scan shows several hot nodules with suppressed uptake elsewhere (Graves disease shows diffuse uptake; a single hot nodule is a toxic adenoma).
- Recurrent laryngeal nerve at thyroidectomy: most at risk at the ligament of Berry, where the gland is attached to the trachea and the nerve runs close to or through it. The tubercle of Zuckerkandl, a posterolateral projection of the lobe at the level of the cricoid, has the RLN deep to it, so it is a reliable guide. A non-recurrent right laryngeal nerve occurs with an aberrant right subclavian artery.
- External laryngeal nerve runs with the superior thyroid artery; injury weakens high-pitched voice.
| Problem after thyroidectomy | Timing and clue | First action |
|---|---|---|
| Haematoma under strap muscles | Hours later: increasing neck swelling, stridor | Open the wound at the bedside (remove sutures and clips) to decompress the airway |
| Bilateral RLN palsy | Stridor at extubation | Reintubate, tracheostomy if needed |
| Hypocalcaemia (parathyroid injury or devascularisation) | Day 1–3: perioral tingling, carpopedal spasm, Chvostek and Trousseau signs | Check serum calcium, give IV calcium gluconate if symptomatic |
Exam trap Stridor hours after thyroidectomy with a swelling neck is haematoma: open the wound before anything else.
Spine, vertebral joints and the spinal needle
- Atlanto-occipital joint allows nodding (flexion and extension); the atlanto-axial joint is a pivot joint (dens in the ring of the atlas) and allows rotation, as when looking left and right. Atlanto-axial instability occurs in rheumatoid arthritis and Down syndrome.
- Eight cervical nerves: C1–C7 exit above their vertebrae, C8 below C7, and all lower nerves exit below theirs.
- Spinal cord ends at L1–L2 in adults (L3 at birth); the dural sac ends at S2.
- Sacral hiatus results from failure of fusion of the laminae of S5 (sometimes S4), bounded by the sacral cornua. Because it lies below the dural sac, a caudal block injects into the epidural space, not the subarachnoid space.
- Lumbar puncture: at L3/L4 or L4/L5, below the cord; the line joining the iliac crests (Tuffier line) crosses L4. The patient lies on the side with knees to chest, because flexion separates the spinous processes and opens the gaps between the laminae.
- Layers crossed: skin, fat, supraspinous ligament, interspinous ligament, ligamentum flavum (loss of resistance), epidural space, dura, arachnoid, then CSF.
- Image the brain first if there are focal signs, papilloedema, seizures or reduced consciousness (risk of coning). Post-dural puncture headache is postural; pencil-point needles reduce it; an epidural blood patch treats it. Normal opening pressure is about 10–20 cmH2O.
Remember Cord ends L1–L2, sac ends S2, needle goes in at L3/L4 or L4/L5.
Cord syndromes and compression
| Syndrome | Features |
|---|---|
| Brown-Séquard (hemisection) | Ipsilateral weakness and loss of vibration and proprioception; contralateral pain and temperature loss |
| Central cord | Arms weaker than legs; cape-like pain and temperature loss in syringomyelia |
| Anterior cord (anterior spinal artery, aortic surgery) | Motor, pain and temperature loss; dorsal columns preserved |
| Posterior columns | Loss of vibration and position sense (B12 deficiency, tabes dorsalis) |
- Disc prolapse is commonest at L4/L5 and L5/S1 and compresses the traversing (lower) root.
- Metastatic cord compression (breast, lung, prostate, kidney, myeloma; thoracic spine commonest): back pain worse lying down, leg weakness, sensory level, sphincter upset; give dexamethasone, arrange urgent whole-spine MRI, then radiotherapy or decompression.
How FCPS asks about this
- Common carotid compressed against: anterior (carotid) tubercle of C6.
- Floor of the posterior triangle and the nerve at risk: muscles covered by prevertebral fascia; superficial accessory nerve.
- Where the RLN is most at risk at thyroidectomy: ligament of Berry; it lies deep to the tubercle of Zuckerkandl.
- Stridor and neck swelling two hours after thyroidectomy: open the wound at the bedside; perioral tingling on day 2 means hypocalcaemia, check calcium.
- Pharyngeal pouch origin: Killian dehiscence in the inferior constrictor.
- Sacral hiatus: failure of fusion of S5 laminae; caudal block is epidural because the dural sac ends at S2.
- Parasympathetic supply for lacrimation: greater petrosal nerve to the pterygopalatine ganglion; rotation of the head occurs at the pivot atlanto-axial joint.
Test yourself on this topic
5 of the 192 questions in our bank on this topic. Choose an answer to see why every option is right or wrong.
After a fish bone is removed from the piriform fossa, a patient coughs and chokes on liquids because sensation above the vocal cords is lost on that side. Which nerve was injured?
Answer: Internal laryngeal nerve
The internal laryngeal nerve (from the superior laryngeal branch of the vagus) pierces the thyrohyoid membrane and runs just beneath the mucosa of the piriform fossa, supplying sensation to the larynx above the vocal folds (and the epiglottis region). Injury abolishes the protective cough reflex, risking aspiration. Below the vocal folds, sensation is via the recurrent laryngeal nerve, which also supplies all intrinsic laryngeal muscles except cricothyroid (external laryngeal nerve). The piriform fossa is a common site for lodged foreign bodies and hypopharyngeal carcinoma.
Laryngeal nerves
- Internal laryngeal: sensation above cords (under piriform fossa mucosa)
- Recurrent laryngeal: below cords + muscles
- External laryngeal: cricothyroid (pitch)
Remember Internal feels above; recurrent moves and feels below.
Why the other options are wrong
- Recurrent laryngeal nerve Sensation below the cords and most muscles.
- External laryngeal nerve Motor to cricothyroid.
- Hypoglossal nerve Tongue movement.
- Glossopharyngeal nerve Pharyngeal sensation and gag, not laryngeal.
A 25-year-old woman in emergency has a regular narrow-complex tachycardia at 180/min. The doctor tries carotid sinus massage after listening for bruits. Where should pressure be applied?
Answer: Below the jaw angle, at upper thyroid cartilage level
The carotid sinus is a dilatation at the start of the internal carotid artery, at the bifurcation of the common carotid. This usually lies at the level of the upper border of the thyroid cartilage (C3–C4), just below and in front of the angle of the mandible, deep to the anterior border of sternocleidomastoid. Its baroreceptors send impulses in the glossopharyngeal nerve, and the reflex increases vagal output, slowing AV node conduction. Massage is done on one side only and avoided if there is a bruit or recent stroke.
Carotid sinus
- At the carotid bifurcation
- Level of upper thyroid cartilage
- Afferent glossopharyngeal
- Efferent vagus slows AV node
Remember Upper thyroid cartilage, just below the jaw angle.
Exam trap Never massage both sides together; it can cause asystole or a stroke.
Why the other options are wrong
- Above the clavicle between the sternocleidomastoid heads This is the site for internal jugular cannulation.
- Over the trachea at the level of the cricoid The carotid lies lateral to the trachea, and this is too low.
- Behind the angle of the jaw over the mastoid The mastoid is above and behind the sinus.
- Low in the neck over the C6 transverse process The C6 tubercle is used to compress the common carotid, below the sinus.
A euthyroid woman has a solitary 2 cm thyroid nodule. TSH is normal. What is the next investigation?
Answer: Ultrasound with FNAC
Approach to a thyroid nodule: check TSH first. If TSH is low (possible toxic adenoma), a radioisotope scan shows a 'hot' nodule, which is rarely malignant. If TSH is normal or high, perform ultrasound; suspicious features (solid, hypoechoic, microcalcifications, irregular margins, taller-than-wide, abnormal nodes) are graded (e.g. U1–U5 or TI-RADS), and fine-needle aspiration cytology is done, reported by Bethesda (Thy) categories. Surgery (lobectomy or total thyroidectomy) depends on cytology. Calcitonin is measured if medullary carcinoma is suspected (family history of MEN 2).
Thyroid nodule
- First: TSH
- Low TSH → isotope scan (hot nodule)
- Normal TSH → ultrasound + FNAC
- Cytology: Bethesda/Thy categories
Remember TSH, then ultrasound, then needle.
Why the other options are wrong
- Isotope scan first Useful mainly if TSH is low.
- Immediate total thyroidectomy Premature without diagnosis.
- CT of the chest Not the next step.
- Serum calcitonin only Only if MTC is suspected.
On a medical ward, a student asks why the JVP is assessed from the right internal jugular rather than the external jugular vein. What is the main reason?
Answer: It runs in a straight line to the right atrium
The right internal jugular vein runs almost straight down through the right brachiocephalic vein and superior vena cava into the right atrium, so its column of blood reflects right atrial pressure and its waveform. The external jugular vein joins the subclavian vein at an angle, passes through the deep fascia where it can be kinked, and has valves, so it can be misleading. The internal jugular is deep to sternocleidomastoid, so its pulsation is seen rather than the vein itself.
JVP
- Right IJV: straight to right atrium
- EJV: angled, valves, kinks
- Seen as double waveform
- Measure from sternal angle
Remember Right IJV is a manometer for the right atrium.
Exam trap The JVP has a double waveform and is not palpable, unlike the carotid pulse.
Why the other options are wrong
- It is more superficial and easier to see The internal jugular is deep to sternocleidomastoid.
- It carries more blood from the face Volume carried does not matter for pressure.
- It has stronger valves in its upper part Valves would interfere, not help.
- It lies outside the deep cervical fascia The internal jugular lies within the carotid sheath.
A heavy smoker with a right apical lung tumour has a hoarse voice, and the right vocal cord does not move. Which of the following structures does the affected nerve normally hook around?
Answer: Right subclavian artery
The right recurrent laryngeal nerve leaves the vagus in the root of the neck, hooks below and behind the right subclavian artery, and ascends in the tracheo-oesophageal groove to the larynx. A tumour at the right lung apex can involve it there, causing ipsilateral vocal cord palsy. The left nerve hooks under the aortic arch beside the ligamentum arteriosum, so it is affected by left hilar tumours, aortic aneurysm or a giant left atrium. Apical tumours may also cause Horner syndrome and arm pain.
Recurrent laryngeal nerves
- Right: hooks under subclavian artery
- Left: hooks under aortic arch
- Left nerve is longer, more often hit
- Palsy: hoarse voice
Remember Right subclavian, left arch.
Exam trap Hoarseness in a smoker may be the first sign of a lung tumour, not a laryngeal one.
Why the other options are wrong
- Arch of the aorta This is the left nerve's loop.
- Ligamentum arteriosum Related to the left nerve.
- Right brachiocephalic vein The nerve passes behind veins but does not hook around them.
- Right common carotid artery The nerve does not loop around the carotid.
Where this sits in the CPSP syllabus
- Medicine & Allied, Paper 2: Regional anatomy for physicians, Head, neck and spine
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