Terlipressin
Variceal bleed: 2 mg IV, then 1–2 mg every 4–6 hours. Also for hepatorenal syndrome with albumin.
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Dose
| Indication | Dose |
|---|---|
| Variceal bleeding | 2 mg IV, then 1–2 mg every 4–6 hours for up to 2–5 days |
| Hepatorenal syndrome | 0.5–1 mg IV every 4–6 hours (or infusion), with albumin (specialist) |
Cautions
- Ischaemia: chest pain, abdominal pain, cold or mottled limbs; avoid in ischaemic heart disease and peripheral vascular disease.
- Low sodium, breathing problems (fluid overload).
Frequently asked questions
Should terlipressin be given before endoscopy?
Yes, in suspected variceal bleeding, along with antibiotics.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.