Propranolol
A non-selective beta-blocker used for migraine prevention, tremor, thyrotoxic symptoms and portal hypertension. Avoid in asthma.
On this page
Dose
| Indication | Dose |
|---|---|
| Migraine prevention | 40 mg 2–3 times daily, or 80–160 mg modified-release daily |
| Thyrotoxicosis symptoms | 10–40 mg 3–4 times daily |
| Portal hypertension (varices) | 40 mg twice daily, adjusted to heart rate (specialist) |
| Essential tremor | 40 mg 2–3 times daily |
Cautions
- Avoid in asthma.
- Slow pulse, low BP, cold hands, tiredness, nightmares.
- Can mask low-sugar symptoms in diabetics.
- Dangerous in overdose.
Frequently asked questions
Can propranolol be used in asthma?
No. It can cause severe bronchospasm.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.
For FCPS Part 1
Revising for FCPS Part 1? Propranolol is covered in our textbook chapter Pharmacokinetics and half-life, with practice MCQs.