Amiodarone
300 mg IV over 20–60 minutes, then 900 mg over 24 hours via a large or central vein. 300 mg IV bolus in shockable cardiac arrest.
On this page
Dose
| Indication | Dose |
|---|---|
| VT or AF (stable) | 300 mg IV in 5% dextrose over 20–60 minutes, then 900 mg over 24 hours |
| After failed shocks (unstable tachycardia) | 300 mg IV over 10–20 minutes |
| Cardiac arrest (VF/pVT) | 300 mg IV after the 3rd shock, 150 mg after the 5th |
| Oral loading | 200 mg 3 times daily for 1 week, twice daily for 1 week, then 200 mg daily |
Cautions
Frequently asked questions
What is the amiodarone dose in cardiac arrest?
300 mg IV after the third shock, and 150 mg after the fifth.
Used in these guides
Sources
Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.
For FCPS Part 1
Revising for FCPS Part 1? Amiodarone is covered in our textbook chapter Drug metabolism, with practice MCQs.