Ofloxacin

A fluoroquinolone used for epididymo-orchitis from urinary organisms, prostatitis and as ear drops.

Fluoroquinolone antibioticReviewed October 2026
On this page

Uses

  • Epididymo-orchitis from urinary (enteric) organisms.
  • Prostatitis.
  • Ear drops for otitis externa and CSOM.

Adult dose

IndicationDose
Epididymo-orchitis200 mg orally twice daily for 14 days
Prostatitis200 mg twice daily for 28 days

Kidney and liver

Reduce in kidney impairment.

Pregnancy and breastfeeding

Avoid in pregnancy.

Side effects and cautions

  • Tendon damage, nerve damage, QT prolongation, low sugar, C. difficile.
  • Separate from antacids and iron.

Frequently asked questions

What is the ofloxacin dose for epididymo-orchitis?

200 mg twice daily for 14 days, when urinary organisms are likely.

Used in these guides

Sources

  1. Drugs.com: Ofloxacin dosage

Doses on this page are typical doses from the sources above. Always confirm with a current drug reference, the product leaflet and your hospital protocol, especially in children, pregnancy and kidney or liver disease.