Diarrhoea and dehydration in children

Weigh the child, grade the dehydration, follow WHO Plan A, B or C, give ORS and zinc, keep feeding, and use antibiotics only for bloody diarrhoea or cholera.

In the paediatric emergency in July

An 11-month-old boy has had watery diarrhoea 8–10 times a day for 2 days and has vomited a few times. He is restless and irritable, drinks eagerly, his eyes are sunken, and a skin pinch goes back slowly. He weighs 8 kg.

How dehydrated is he, and how much ORS do you give?

Do now: in this order
  1. Danger signs firstLethargic or unconscious, cannot drink, fits, shock. Severe dehydration: Plan C now.
  2. Weigh the childEvery volume is calculated by weight.
  3. Grade the dehydrationNo, some or severe (WHO signs below).
  4. Follow Plan A, B or CORS by mouth or NG for most children. IV only for severe dehydration.
  5. Zinc for every childFor 10–14 days.
  6. Keep feedingContinue breastfeeding and normal food.
  7. Check for other problemsMalnutrition, blood in stool, fever, low sugar, other infections.
  8. Teach the motherHow to give ORS, danger signs, when to return.
Call your senior if
  • Severe dehydration or shock
  • Lethargic or unconscious
  • Cannot drink or vomiting everything
  • Severe acute malnutrition
  • Blood in stool with fever
  • Diarrhoea for more than 14 days
Don’t miss
  • Shock
  • Severe acute malnutrition (different fluid rules)
  • Low sugar
  • Sodium or potassium problems
  • Intussusception, sepsis, UTI or a surgical abdomen
Key numbers
Plan A (no dehydration)ORS after each loose stool: under 2 years 50–100 mL, 2 years and over 100–200 mL
Plan B (some dehydration)ORS 75 mL/kg over 4 hours, then reassess
Plan C (severe)Ringer's lactate 100 mL/kg IV: under 12 months 30 mL/kg over 1 hour then 70 mL/kg over 5 hours, 12 months and over 30 mL/kg over 30 minutes then 70 mL/kg over 2.5 hours
Zinc10 mg daily under 6 months, 20 mg daily from 6 months, for 10–14 days
Severe malnutritionDifferent, slower rehydration. Do not use Plan C

Check every dose against a current drug reference and your hospital protocol.

On this page

Why it matters

Diarrhoea remains a major cause of death in children under 5 in Pakistan, especially in summer and the monsoon. Almost all of these deaths are from dehydration and are preventable with ORS, zinc and continued feeding.

Grading dehydration (WHO)

Look at the child
Two or more signs from one column
Severe dehydration
  • Lethargic or unconscious
  • Sunken eyes
  • Drinks poorly or cannot drink
  • Skin pinch goes back very slowly (2 seconds or more)
  • Plan C
Some dehydration
  • Restless, irritable
  • Sunken eyes
  • Drinks eagerly, thirsty
  • Skin pinch goes back slowly
  • Plan B
No dehydration
  • Not enough signs for some or severe
  • Plan A

In the case: restless, sunken eyes, drinks eagerly, slow skin pinch = some dehydration: Plan B. 75 mL/kg × 8 kg = 600 mL of ORS over 4 hours.

Plan A: treat at home

  • ORS after each loose stool: under 2 years 50–100 mL, 2 years and over 100–200 mL.
  • Zinc for 10–14 days.
  • Continue feeding and breastfeeding. Give more fluids than usual.
  • Return immediately if: not drinking or feeding, getting more unwell, fever, blood in stool, sunken eyes.

Plan B: ORS in the clinic

  • ORS 75 mL/kg over 4 hours, given little and often with a cup and spoon.
  • If the child vomits, wait 10 minutes, then continue more slowly.
  • Continue breastfeeding.
  • Reassess after 4 hours and choose Plan A, B or C again.
  • If the child cannot drink, give ORS by NG tube at the same rate.

Plan C: severe dehydration

Plan C (WHO)
  1. IV access nowTwo attempts at IV. If not possible, intraosseous, or ORS by NG tube 20 mL/kg/hour for 6 hours.
  2. Ringer's lactate 100 mL/kgUnder 12 months: 30 mL/kg over 1 hour, then 70 mL/kg over 5 hours.
  3. Older children12 months and over: 30 mL/kg over 30 minutes, then 70 mL/kg over 2.5 hours.
  4. Repeat the first 30 mL/kgIf the radial pulse is still weak or absent.
  5. Reassess every 1–2 hoursSpeed up if not improving.
  6. Start ORS as soon as the child can drinkAbout 5 mL/kg/hour.
  7. Reassess at the endChoose Plan A, B or C.
Caution

Severe acute malnutrition (visible severe wasting, swelling of both feet, very low weight or MUAC below 11.5 cm): do not use Plan C or standard ORS. These children are at high risk of heart failure from fluid. Follow the severe malnutrition protocol (ReSoMal, slower rates, IV fluids only for shock).

Medicines

RxDiarrhoea in children
Oral rehydration salts (ORS)Plan A: 50–200 mL after each stool. Plan B: 75 mL/kg over 4 hoursLow-osmolarity ORS. Mix one sachet in the volume of clean water written on the packet Dose source: MSF Essential Drugs: Oral rehydration salts
Zinc10 mg daily under 6 months, 20 mg daily from 6 months, for 10–14 daysReduces duration and future episodes Dose source: WHO: The treatment of diarrhoea, a manual for physicians
Ringer's lactate100 mL/kg IV (Plan C, as above)Severe dehydration Dose source: Drugs.com: Lactated Ringer's dosage
Azithromycin10–20 mg/kg by mouth once daily for 3 daysDysentery (blood in stool). Shigella is often resistant to ciprofloxacin in Pakistan. Follow local guidance Dose source: Drugs.com: Azithromycin dosage
Ondansetron0.15 mg/kg by mouth (maximum 4 mg), single doseOnly for persistent vomiting preventing ORS, over 6 months Dose source: Drugs.com: Ondansetron dosage
If ORS sachets are not available

Home-made solution: 1 litre of clean boiled and cooled water + 6 level teaspoons of sugar + half a level teaspoon of salt. Measure carefully: too much salt is dangerous. Use packet ORS as soon as possible.

What not to give

Avoid these medicines
  • Antidiarrhoeals (loperamide, diphenoxylate): dangerous in children.
  • Routine antibiotics or metronidazole for watery diarrhoea: most is viral. Antibiotics are only for bloody diarrhoea (dysentery), suspected cholera, or another infection.
  • Routine antiemetic injections (such as promethazine).
  • Fruit juices, sugary drinks and soft drinks instead of ORS: they can worsen diarrhoea.
  • Stopping breastfeeding or food.

When it is not just gastroenteritis

  • Blood in stool with fever: dysentery (Shigella). Antibiotic.
  • Rice-water stools with severe dehydration in an outbreak: cholera. Antibiotic and urgent rehydration.
  • Diarrhoea for more than 14 days: persistent diarrhoea. Check for malnutrition, infection, HIV.
  • Bilious vomiting, blood and mucus ("redcurrant jelly") stool, a mass: intussusception. Surgical review.
  • High fever, very unwell: sepsis, UTI, malaria, pneumonia.

Common mistakes

Avoid these
  • Not weighing the child.
  • Running IV fluids for some dehydration when ORS would work.
  • Using Plan C in a severely malnourished child.
  • Prescribing metronidazole syrup or loperamide for watery diarrhoea.
  • Forgetting zinc.
  • Telling the mother to stop feeding.

Frequently asked questions

How much ORS should be given for some dehydration?

75 mL/kg over 4 hours (WHO Plan B), then reassess.

What is the zinc dose for diarrhoea in children?

10 mg daily under 6 months and 20 mg daily from 6 months, for 10–14 days.

What is WHO Plan C?

For severe dehydration: Ringer's lactate 100 mL/kg IV. Under 12 months, 30 mL/kg over 1 hour then 70 mL/kg over 5 hours. 12 months and older, 30 mL/kg over 30 minutes then 70 mL/kg over 2.5 hours.

When are antibiotics needed for diarrhoea in children?

For bloody diarrhoea (dysentery), suspected cholera, or another bacterial infection. Most watery diarrhoea is viral and does not need antibiotics.

Test yourself

Exam-style questions on this guide, from our two question banks. Choose an answer to see why each option is right or wrong.

NRE-1 PrepClinical MCQs, PMDC NRE style

1. A child with diarrhoea has some dehydration. Which WHO plan is used?

2. A child has bloody diarrhoea and fever. Which antibiotic is preferred in Pakistan?

3. A severely wasted child has diarrhoea and some dehydration. What fluid approach is used?

4. A 22-year-old student develops acute watery diarrhoea 3 days into a trip, without blood or fever. He is drinking well. What is the main treatment?

5. A 14-month-old (10 kg) with watery diarrhoea is restless, has sunken eyes and drinks eagerly; skin pinch returns slowly. What is the treatment?

FCPS-1 PrepBasic science MCQs for CPSP FCPS Part 1

6. Which receptors are most abundant in the fingertips and detect light touch and two-point discrimination?

7. A child has a swollen belly, pitting oedema of the legs, flaky skin, light-coloured hair streaks and a large liver. What is the diagnosis?

References and dose sources

  1. WHO: The treatment of diarrhoea, a manual for physicians and other senior health workers
  2. WHO fact sheet: Diarrhoeal disease
  3. Oral rehydration salts (ORS) dosing: MSF Essential Drugs: Oral rehydration salts (see also our oral rehydration salts (ors) dose page)
  4. Zinc dosing: WHO: The treatment of diarrhoea, a manual for physicians (see also our zinc dose page)
  5. Ringer's lactate (Hartmann's solution) dosing: Drugs.com: Lactated Ringer's dosage (see also our ringer's lactate (hartmann's solution) dose page)
  6. Dextrose (glucose) dosing: Drugs.com: Dextrose dosage (see also our dextrose (glucose) dose page)
  7. Azithromycin dosing: Drugs.com: Azithromycin dosage (see also our azithromycin dose page)
  8. Ondansetron dosing: Drugs.com: Ondansetron dosage (see also our ondansetron dose page)

International guidance is linked where it reflects good practice. Where your hospital’s protocol differs, follow your hospital.